RÔLE OF GLUTAMINE IN PROTEIN SYNTHESIS BY THE EHRLICH ASCITES CARCINOMA
نویسندگان
چکیده
منابع مشابه
Effects of Ehrlich ascites antisera on the biochemical activities of Ehrlich ascites carcinoma cells in vitro.
Anl i-tumor sera are now being extensively used in investigations of the activities of neoplasms (e.g. 4-7, 9-13, 15). I t is already known (7), concerning their effects on the biochemical activities of tumors, that Ehrlich ascites carcinoma cells, treated with their antisera in the presence of comp]ement, lose their capacity to respire in the presence of glucose but not in the presence of succ...
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The inhibition of tumor growth and tumor induced angiogenesis by the glutamine antimetabolite acivicin was evaluated in 6-7 weeks old male Swiss albino mice bearing Ehrlich ascites carcinoma (EAC) transplanted by intraperitoneal (ip) injections of EAC cells. Treatment involving ip injections with two different doses of acivicin (0.05 and 0.41microg/g body weight/day) in saline revealed decrease...
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Several attempts in this laboratory in the last @ or 3 years to culture the Knebs-@ ascites carcinoma of mice had failed. The maximum survival time of the cells in culture was about 10 days. The media used always contained chicken embryo ex tract (CEE). Later, during efforts to develop a culture medium and technic by which single cell cultures could readily be initiated for single-cell irradiat...
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Puromycin is a broad spectrum antibiotic for various microorganisms, parasitic worms, and some transplanted animal tumors (2). It has been shown to interfere with adaptive enzyme formation (3) and protein synthesis (4) in bacteria and also to inhibit incorporation of labeled amino acids into protein by a cell-free system of liver ribosomes (5)) Escherichiu coli ribosomes (6), and thymus nuclei ...
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The effect of viruses on malignant tumors has been examined by a number of investigators (9). With the conversion of solid tumors into ascites form (8), however, it has become possible to carry out a more definitive study of the growth of viruses in cancer cells. The present communication deals with the normal growth characteristics of a hyperdiploid line of the Ehrlich ascites carcinoma of the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1956
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(20)89945-1